EXCALIBER RRMM

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

What's the purpose of the trial?

This is a multicenter, randomized, controlled, open-label, Phase 3 study comparing the efficacy and safety of iberdomide in combination with dexamethasone and daratumumab (IberDd) versus daratumumab, bortezomib, and dexamethasone (DVd) in participants with relapsed or refractory multiple myeloma (RRMM).

Trial status

Accepting patients

Phase
Phase 3
Enrollment
864
Last Updated
4 days ago
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Participating Centers

There are 32 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • Bortezomib
  • Daratumumab
  • Dexamethasone
  • Iberdomide

Arms / Cohorts

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Accepting patients

Iberdomide + Daratumumab + Dexamethasone

Accepting patients

Daratumumab + Bortezomib + Dexamethasone

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