SUCCESSOR-1

A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing CC-92480, Bortezomib and Dexamethasone (480Vd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Subjects with Relapsed or Refractory Multiple Myeloma (RRMM)

What's the purpose of the trial?

The goal of this clinical trial is to learn more about the safety and effectiveness of investigational drug mezigdomide given in combination with Bortezomib and Dexamethasone. Researchers will compare this investigational combination against standard of care treatments Pomalidomide, Bortezomib and Dexamethasone to learn more about how mezigdomide works in relapsed or refractory multiple myeloma.

Trial status

Accepting patients

Phase
Phase 3
Enrollment
810
Last Updated
1 week ago
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Participating Centers

There are 35 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • Bortezomib
  • Dexamethasone
  • Mezigdomide
  • Pomalidomide

Arms / Cohorts

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Accepting patients

Mezigdomide + Bortezomib + Dexamethasone

Accepting patients

Pomalidomide + Bortezomib + Dexamethasone

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